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| Year : 2007 | Volume
: 1
| Issue : 3 | Page : 81 |
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EDITORIAL Biological trends in shoulder surgery
Deepak N Bhatia, Joe F de Beer
Cape Shoulder Institute, Suite 4, Medgroup Anlin House, 43 Bloulelie Crescent, Platekloof, PO box 15746, Panorama 7506, Cape Town, South Africa
Correspondence Address:
Deepak N Bhatia
Cape Shoulder Institute, Suite 4, Medgroup Anlin House, 43 Bloulelie Crescent, Platekloof, PO box 15746, Panorama 7506, Cape Town
South Africa
DOI: 10.4103/0973-6042.34755 |
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How to cite this article:
Bhatia DN, de Beer JF. Biological trends in shoulder surgery. Int J Shoulder Surg 2007;1:81 |
The biological era is here. Biological augmentations, repairs, replacements and resurfacings are undergoing investigation and basic science is playing a part, more than ever before, in medical and surgical solutions. Autologous cell regeneration and acellular biological scaffolds have recently generated considerable interest in orthopaedic disorders. Some of these techniques have found applications in shoulder surgery. [1],[2],[3] Within the shoulder, augmentation and repair of rotator cuff defects, resurfacing arthritic surfaces and cuff replacement, with biological tissues, have been suggested as alternatives to conventional synthetics and prosthetics. At present, most procedures that involve use of biological tissues are under investigation by the innovators, inventors and laboratory scientists. Yet, techniques and equipment are fast developing to enable surgeons to perform these procedures in a least invasive manner, even arthroscopic. Legal restrictions, technical expertise and lack of scientific studies with longer follow-up periods, need to be overcome before these therapies gain widespread acceptability.
In the previous issues of the International Journal of Shoulder Surgery, two important aspects of biological techniques in shoulder surgery were published. [1],[2] In the first issue, Dopirak et al. , presented their series and an arthroscopic technique of using an acellular human dermal allograft matrix for rotator cuff replacement in irreparable rotator cuff tears. [1] In the second issue, du Toit et al. , reviewed the relevant literature on the molecular biology of platelet-rich plasma and its use in tissue augmentation. [2] With the current issue, we begin a multi-part series of review articles on the basic science of biological tissues and possible implications in shoulder surgery. In the first article of the series , the basic science of the human fibroblast and myofibroblast is presented and the possible role of these cells in shoulder pathology is discussed. [3]
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| 1. | Dopirak R, Bond JL, Snyder SJ. Arthroscopic total rotator cuff replacement with an acellular human dermal allograft matrix. Int J Shoulder Surg 2007;1:7-15.   |
| 2. | Du Toit DF, Kleintjes WG, Otto MJ, Mazyala EJ, Page BJ. Soft and hard-tissue augmentation with platelet-rich plasma: Tissue culture dynamics, regeneration and molecular biology perspective. Int J Shoulder Surg 2007;1:64-73. |
| 3. | Du Toit DF, Kleintjes WG, Mazyala EJ, Bhatia DN, De Beer JF, Page BJ. Shoulder surgeon and autologous cellular regeneration (ACR) - From bench to bed: Part one- the link between the human fibroblast, connective tissue disorders and shoulder. Int J Shoulder Surg 2007;1:87-95. |
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